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Artesunate
$60 – $96
Products Details
Product Description
– Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
Web ID
– HY-N0193
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H28O8
References
– [1]Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56.|[2]Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63.|[3]Lisewski AM, et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928.
CAS Number
– 88495-63-0
Molecular Weight
– 384.42
Compound Purity
– 98.09
SMILES
– O=C(O[C@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1)CCC(O)=O
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– 7.5% sodium bicarbonate : 20 mg/mL (ultrasonic)|DMSO : 83.33 mg/mL (ultrasonic)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Ferroptosis;Parasite;STAT;Virus Protease
Isoform
– STAT3
Pathway
– Anti-infection;Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
