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Artemisinin
SKU
HY-B0094-10mM/1mL
Category Natural Products
Tags Akt;Ferroptosis;HCV;Parasite, Anti-infection;Apoptosis;PI3K/Akt/mTOR, Cancer; Infection; Neurological Disease
$70 – $100
Products Details
Product Description
– Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
Web ID
– HY-B0094
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H22O5
References
– [1]Zeng Z, et al. Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol. 2017 Apr 4;12:625-633.|[2]Lin SP, et al. Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation. Front Cell Neurosci. 2018 Apr 20;12:108.
CAS Number
– 63968-64-9
Molecular Weight
– 282.33
Compound Purity
– 99.03
SMILES
– O=C1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1
Clinical Information
– Launched
Research Area
– Cancer; Infection; Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
Target
– Akt;Ferroptosis;HCV;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Apoptosis;PI3K/Akt/mTOR
Product type
– Natural Products
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