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Products Details
Product Description
– ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively[1].
Web ID
– HY-148710
Shipping
– Room temperature
Molecular Formula
– C12H13N3O3
References
– [1]Ekblad T, et al. Towards small molecule inhibitors of mono-ADP-ribosyltransferases. Eur J Med Chem. 2015 May 5;95:546-51.
CAS Number
– 1708103-69-8
Molecular Weight
– 247.25
SMILES
– CNC(/C=CC(NC1=CC(C(N)=O)=CC=C1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PARP
Isoform
– PARP1;PARP10;PARP14;PARP15
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
