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Products Details
Product Description
– ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively[1].
Web ID
– HY-143338
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H13NO2S
References
– [1]Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021;52:116511.
CAS Number
– 2418014-98-7
Molecular Weight
– 259.32
SMILES
– CC(OC1=CC2=C(C(NC3=C2C=CS3)=O)C=C1)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PARP
Isoform
– PARP10;PARP14;PARP15;PARP2;TNKS2/PARP5B
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
