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Products Details
Product Description
– ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].
Web ID
– HY-101535
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H26N2O5S
References
– [1]Jo YK, et al. ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. Biochem Biophys Res Commun. 2011;404(4):1039-1043.
CAS Number
– 849773-63-3
Molecular Weight
– 406.50
SMILES
– CC(C)[C@@H](N(S(=O)(C1=CC=C(C2=CC=CC=C2)C=C1)=O)OC(C)C)C(NO)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
