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Argininosuccinic acid (disodium)
$230 – $370
Products Details
Product Description
– Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].
Web ID
– HY-113149A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Molecular Formula
– C10H16N4Na2O6
References
– [1]Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244.|[2]Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.
CAS Number
– 918149-29-8
Molecular Weight
– 334.24
Compound Purity
– 96.0
SMILES
– OC([C@@H](N)CCCNC(N[C@H](C(O[Na])=O)CC(O[Na])=O)=N)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
