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Arginase inhibitor 1
$317 – $3,432
Products Details
Product Description
– Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.
Web ID
– HY-15775
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H27BN2O4
References
– [1]Van Zandt MC, et al. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potentinhibitors of human arginases I and II for treatment of myocardial reperfusion injury. J Med Chem. 2013 Mar 28;56(6):2568-80.
CAS Number
– 1345808-25-4
Molecular Weight
– 286.18
Compound Purity
– 98.0
SMILES
– O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 48 mg/mL|H2O : ≥ 30 mg/mL
Target
– Arginase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
