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Products Details
Product Description
– Argatroban-d3 is the deuterium labeled Argatroban. Argatroban (MD-805) is a direct, selective thrombin inhibitor.
Web ID
– HY-B0375S
Shipping
– Room temperature
Molecular Formula
– C23H33D3N6O5S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.|[3]Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9.
CAS Number
– 1356847-56-7
Molecular Weight
– 511.65
SMILES
– O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(CC(CN3)C([2H])([2H])[2H])=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Isotope-Labeled Compounds;Thrombin
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
