Products Details

Product Description

– Ara-F-NAD+ sodium is an arabino analogue of NAD+. Ara-F-NAD+ sodium is a potent, reversible and slow-binding CD38 NADase inhibitor[1][2].

Web ID

– HY-134358A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Molecular Formula

– C21H25FN7NaO13P2

References

– [1]Berthelier V, et al. Human CD38 is an authentic NAD(P)+ glycohydrolase. Biochem J. 1998;330 ( Pt 3)(Pt 3):1383-1390.|[2]Wang S, et al. Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. Molecules. 2014;19(10):15754-15767. Published 2014 Sep 29.

Molecular Weight

– 687.40

Compound Purity

– 99.0

SMILES

– O[C@H]1[C@]([H])(N2C3=NC=NC(N)=C3N=C2)O[C@H](COP(OP(OC[C@H]4O[C@]([H])([C@H](F)[C@@H]4O)[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)([O-])=O)[C@H]1O.[Na+]

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– CD38

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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