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Products Details
Product Description
– Ara-F-NAD+ is an arabino analogue of NAD+. Ara-F-NAD+ is a potent, reversible and slow-binding CD38 NADase inhibitor[1][2].
Web ID
– HY-134358
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H26FN7O13P2
References
– [1]Berthelier V, et al. Human CD38 is an authentic NAD(P)+ glycohydrolase. Biochem J. 1998;330 ( Pt 3)(Pt 3):1383-1390. doi:10.1042/bj3301383|[2]Wang S, et al. Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. Molecules. 2014;19(10):15754-15767. Published 2014 Sep 29.
CAS Number
– 133575-27-6
Molecular Weight
– 665.42
SMILES
– O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(OC[C@H]2O[C@]([N+]3=CC=CC(C(N)=O)=C3)([H])[C@H]([C@@H]2O)F)([O-])=O)(O)=O)([H])N4C5=NC=NC(N)=C5N=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– CD38
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
