AR420626

$90$850

Products Details

Product Description

– AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats[1].

Web ID

– HY-116522

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C21H18Cl2N2O3

References

– [1]Kaji I, et al. Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon. Neurogastroenterol Motil. 2018 Jan;30(1):10.1111/nmo.13157.

CAS Number

– 1798310-55-0

Molecular Weight

– 417.29

Compound Purity

– 98.58

SMILES

– ClC1=CC(NC(C2=C(NC(CCC3)=C(C2C4=CC=CO4)C3=O)C)=O)=C(C=C1)Cl

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Free Fatty Acid Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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