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Products Details
Product Description
– AR-A014418-d3 is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].
Web ID
– HY-10512S
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C12H9D3N4O4S
References
– [1]Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278(46):45937-45.
CAS Number
– 1216908-63-2
Molecular Weight
– 311.33
SMILES
– O=C(NCC1=CC=C(OC([2H])([2H])[2H])C=C1)NC2=NC=C([N+]([O-])=O)S2
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– GSK-3;Isotope-Labeled Compounds
Pathway
– Others;PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
