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Products Details
Product Description
– APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1].
Web ID
– HY-131542
Shipping
– Room temperature
Molecular Formula
– C14H13NO3
References
– [1]Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487.
CAS Number
– 100750-39-8
Molecular Weight
– 243.26
SMILES
– CC(N1C(C2=CC=CC=C2)=CC(OC(C)=O)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Aldose Reductase;Apoptosis
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
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