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Products Details
Product Description
– Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4].
Web ID
– HY-N0088S
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C9H7D3O3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102.|[3]Stefanska J, et al. Mediators Inflamm, 2008, 106507.|[4]Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 181(5):636-48.
CAS Number
– 80404-23-5
Molecular Weight
– 169.19
SMILES
– [2H]C([2H])([2H])OC1=CC(C(C)=O)=CC=C1O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy
Pathway
– Apoptosis;Autophagy
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
