Download Files:
Products Details
Product Description
– APJ receptor agonist 3 is a potent and orally active APJ receptor agonist with an EC50 value of 0.027 nM.
Web ID
– HY-139876
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H29ClN4O5
References
– [1]Pi Z, et al. Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists. ACS Med Chem Lett. 2021 Oct 22;12(11):1766-1772.
CAS Number
– 2759159-56-1
Molecular Weight
– 512.99
SMILES
– CCCCC(N(C1=C(C=CC=C1OC)OC)C(O)=C2C(N3C[C@H](C4=CC=C(C=N4)Cl)CC3)=O)=NC2=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Apelin Receptor (APJ)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
