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Apigenin
$35 – $264
Products Details
Product Description
– Apigenin (4′,5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
Web ID
– HY-N1201
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H10O5
References
– [1]Si D, et al. Mechanism of CYP2C9 inhibition by flavones and flavonols. Drug Metab Dispos. 2009 Mar;37(3):629-34.|[2]Wu K, et al. Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells. World J Gastroenterol. 2005 Aug 7;11(29):4461-4.|[3]Yu W, et al. Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway. Evid Based Complement Alternat Med. 2017;2017:2590676.
CAS Number
– 520-36-5
Molecular Weight
– 270.24
Compound Purity
– 99.58
SMILES
– OC1=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=CC(O)=C1
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
Target
– Autophagy;Cytochrome P450;Endogenous Metabolite
Isoform
– CYP2
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
