AP521

$170$1,700

Products Details

Product Description

– AP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM.

Web ID

– HY-100166

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture and light)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H19ClN2O3S

References

– [1]Kasahara K, et al. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. J Pharmacol Sci. 2015 Jan;127(1):109-16.

CAS Number

– 151227-08-6

Molecular Weight

– 402.89

Compound Purity

– 98.96

SMILES

– O=C([C@H]1CC(C2=CC=CC=C2S3)=C3CN1)NCC4=CC=C(OCO5)C5=C4.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 25 mg/mL (ultrasonic)

Target

– 5-HT Receptor

Isoform

– 5-HT1 Receptor;5-HT5 Receptor;5-HT7 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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