AP1867

$450$3,350

Products Details

Product Description

– AP1867 is a synthetic FKBP12F36V-directed ligand[1].

Web ID

– HY-114434

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C38H47NO11

References

– [1]Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.|[2]Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408.

CAS Number

– 195514-23-9

Molecular Weight

– 693.78

Compound Purity

– 99.43

SMILES

– COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)C4=CC=CC(OCC(O)=O)=C4)C=C1OC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– FKBP

Pathway

– Apoptosis;Autophagy;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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