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AP1867
SKU
HY-114434-10 mg
Category Reference compound
Tags Apoptosis;Autophagy;Immunology/Inflammation, Cancer, FKBP
$450 – $3,350
Products Details
Product Description
– AP1867 is a synthetic FKBP12F36V-directed ligand[1].
Web ID
– HY-114434
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H47NO11
References
– [1]Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.|[2]Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408.
CAS Number
– 195514-23-9
Molecular Weight
– 693.78
Compound Purity
– 99.43
SMILES
– COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)C4=CC=CC(OCC(O)=O)=C4)C=C1OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– FKBP
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.