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Products Details
Product Description
– Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo[1].
Web ID
– HY-147521
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H34N4O4
References
– [1]Gao YH, et al. Synthesis and pharmacological evaluation of chlorin derivatives for photodynamic therapy of cholangiocarcinoma. Eur J Med Chem. 2020 Mar 1;189:112049.
Molecular Weight
– 730.81
SMILES
– COC(C1(C2/C(N=C(C21)/C(C3=CC=CC=C3)=C4C=C/C(N/4)=C5C6=CC=CC=C6)=C(C7=CC=CC=C7)/C(N8)=CC=C8/C(C9=CC=CC=C9)=C%10C=CC5=N/%10)C(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Necroptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
