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Product Description
– Antitumor agent-64 (Compound 8d) is a diosgenin derivative. Antitumor agent-64 exhibits potent cytotoxic activity against A549 cell line. Antitumor agent-64 induces A549 cells apoptosis via the mitochondria-related pathway[1].
Web ID
– HY-147538
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H47N3O3S
References
– [1]Zhang J, et al. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation. Eur J Med Chem. 2020 Jan 15;186:111897.
CAS Number
– 2396562-55-1
Molecular Weight
– 589.83
SMILES
– C[C@@]12[C@]3([H])[C@](O[C@@H]([C@H]3C)CC[C@H](C4=NN=C(C5=CN=CC=C5)S4)C)([H])C[C@@]1([H])[C@@]6([H])[C@]([C@@]7(C(C[C@H](CC7)OC(C)=O)=CC6)C)([H])CC2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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