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Products Details
Product Description
– Antitumor agent-55 (compound 5q) is a potent antitumor agent. Antitumor agent-55 effectively inhibits PC3, with an IC50 of 0.91 μM. Antitumor agent-55 effectively inhibits the colony formation, suppresses the cell migration in PC3. Antitumor agent-55 induces G1/S phase arrest and apoptosis in PC3[1].
Web ID
– HY-146038
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H34N6O4S
References
– [1]Lu N, Huo JL, Wang S, Yuan XH, Liu HM. Drug repurposing: Discovery of troxipide analogs as potent antitumor agents. Eur J Med Chem. 2020;202:112471.
CAS Number
– 2522594-49-4
Molecular Weight
– 598.72
SMILES
– O=C(NC1CN(C2=CC(C)=NC3=NC(SCC4=C5C=CC=CC5=CC=C4)=NN23)CCC1)C6=CC(OC)=C(OC)C(OC)=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Bcl-2 Family;MDM-2/p53;ROS Kinase
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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