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Products Details
Product Description
– Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells[1].
Web ID
– HY-144394
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H17BrFN5O3
References
– [1]Jianqing Zhang, et al. Synthesis, bioevaluation and molecular dynamics of pyrrolo-pyridine benzamide derivatives as potential antitumor agents in vitro and in vivo. Eur J Med Chem. 2022 Apr 5;233:114215.
CAS Number
– 2581082-74-6
Molecular Weight
– 570.37
SMILES
– O=C(C1=CN(C2=NC=CC=C2C1=O)C3=CC=C(C=C3)Br)NC4=CC=C(C(F)=C4)OC5=CC=NC6=C5C=CN6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;c-Met/HGFR
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
