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Antitumor agent-42
SKU
HY-144331-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton, Apoptosis;Microtubule/Tubulin, Cancer
Products Details
Product Description
– Antitumor agent-42 (Compound 15h) is a bifunctional agent exhibiting both tubulin polymerized inhibition and NO-releasing activities, resulting in potent anti-angiogenesis, colony formation inhibition, cell cycle arrest and apoptosis induction effects[1].
Web ID
– HY-144331
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H19BrN2O8S
References
– [1]Xin Huang, et al. Synthesis and biological evaluation of novel hybrids of phenylsulfonyl furoxan and phenstatin derivatives as potent anti-tumor agents. Eur J Med Chem. 2022 Feb 15; 230:114112.
CAS Number
– 2763621-91-4
Molecular Weight
– 575.39
SMILES
– COC1=CC=C(C=C1OCCOC2=NO[N+]([O-])=C2S(=O)(C3=CC=CC=C3)=O)C(C4=CC=C(C=C4)Br)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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