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Antitrypanosomal agent 19
Products Details
Product Description
– Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice[1].
Web ID
– HY-163003
Shipping
– Room temperature
Molecular Formula
– C10H11N3O4S
References
– [1]Ajayi O et al. Discovery of an orally active nitrothiophene-based antitrypanosomal agent[J]. European Journal of Medicinal Chemistry, 2023: 115954.
Molecular Weight
– 269.28
SMILES
– O=C(C1=CC=C([N+]([O-])=O)S1)NC/C=C/C(NC)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
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