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Products Details
Product Description
– Antitrypanosomal agent 13 (compound 4b) is a potent antitrypanosomal agent. Antitrypanosomal agent 13 has trypanocidal and cytotoxic activity with GI50 values of 0.18 and 8.4 μM for T. brucei and HL-60, respectively[1].
Web ID
– HY-149986
Shipping
– Room temperature
Molecular Formula
– C47H81N2NaO10S
References
– [1]Antoszczak M, et, al. Synthesis of urea and thiourea derivatives of C20-epi-aminosalinomycin and their activity against Trypanosoma brucei. Eur J Med Chem. 2023 Mar 15;250:115241.
Molecular Weight
– 889.21
SMILES
– CC[C@H]([C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(CC[C@H](NC(NCCCC)=S)[C@@]3(O[C@@]([C@@H]4O[C@@H](C)[C@@](O)(CC)CC4)(C)CC3)O2)O1)C([C@H]([C@@H](O)[C@H](C)[C@]5([H])O[C@@H]([C@H](C(O[Na])=O)CC)CC[C@@H]5C)C)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
