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Products Details
Product Description
– Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis[1].
Web ID
– HY-146103
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H32N4O
References
– [1]Dheer D,et al.Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents. Eur J Med Chem. 2020 Dec 1;207:112813.
CAS Number
– 2497687-47-3
Molecular Weight
– 440.58
SMILES
– CCN(CC)CCCOC1=CC=C(C2=C(C3=CC=CC=C3)N=NN2CC4=CC=CC=C4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Reactive Oxygen Species
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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