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Products Details
Product Description
– Antiproliferative agent-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative agent-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative agent-5 can be used for researching anticancer[1].
Web ID
– HY-146390
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H21BrN8OS
References
– [1]Wang S, et al. Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway. Eur J Med Chem. 2020;203:112630.
CAS Number
– 2459892-41-0
Molecular Weight
– 597.49
SMILES
– O=C(C1=CC=C(NC2=CC(C)=NC3=NC(SCC4=NC5=CC=CC=C5N4)=NN23)C=C1)/C=C/C6=NC(Br)=CC=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;Reactive Oxygen Species
Pathway
– Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
