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Antiproliferative agent-14
$180 – $1,350
Products Details
Product Description
– Antiproliferative agent-14 (compound 3b) a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle[1].
Web ID
– HY-148265
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C21H18FN3O2
References
– [1]An W, et al. Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents. Eur J Med Chem. 2016 Apr 13;112:367-372.
CAS Number
– 1885900-35-5
Molecular Weight
– 363.38
Compound Purity
– 98.76
SMILES
– COC1=CC=C(C=C1)CNC2=C(N=C3C=CC(F)=CN32)C4=C(C=CC=C4)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
