Antiproliferative agent-14

$180$1,350

Products Details

Product Description

– Antiproliferative agent-14 (compound 3b) a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle[1].

Web ID

– HY-148265

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Molecular Formula

– C21H18FN3O2

References

– [1]An W, et al. Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents. Eur J Med Chem. 2016 Apr 13;112:367-372.

CAS Number

– 1885900-35-5

Molecular Weight

– 363.38

Compound Purity

– 98.76

SMILES

– COC1=CC=C(C=C1)CNC2=C(N=C3C=CC(F)=CN32)C4=C(C=CC=C4)O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 100 mg/mL

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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