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Products Details
Product Description
– Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].
Web ID
– HY-146042
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H13N3O2
References
– [1]Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.
CAS Number
– 2253996-66-4
Molecular Weight
– 279.29
SMILES
– OC(C(C1=NC(C2=CC=CC=C2)=NO1)=C)C3=CC=CN=C3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania;Trypanosoma
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
