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Products Details
Product Description
– Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide targeting mycobacterial electron transport chain (ETC) airway CIII2CIV2 supercomplexes. The IC50 value of Antimycobacterial agent-5 against Mycobacterium smegmatisCIII2CIV2 is 441 nM[1].
Web ID
– HY-149998
Shipping
– Room temperature
Molecular Formula
– C25H34ClN3O
References
– [1]Rana Abdelaziz, et al. Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity. ACS Omega. 2023 May 18;8(21):19081-19098.
Molecular Weight
– 428.01
SMILES
– ClC(C=C1)=CN2C1=NC(CC)=C2C(NC/C=C(C)/CC/C=C(C)/CC/C=C(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Bacterial;Reactive Oxygen Species
Pathway
– Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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