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Products Details
Product Description
– Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines[1].
Web ID
– HY-146078
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H21N3O2S
References
– [1]Dokla EME, et al. Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. Eur J Med Chem. 2020;186:111850.
CAS Number
– 2579696-45-8
Molecular Weight
– 391.49
SMILES
– CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
