Download Files:
Antileishmanial agent-8
Products Details
Product Description
– Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].
Web ID
– HY-147536
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H16O4
References
– [1]Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.
CAS Number
– 2477608-96-9
Molecular Weight
– 296.32
SMILES
– O=C(O)/C=C/C1=CC=C(OC(C2=CC=C(O)C=C2)C3C)C3=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.