Antileishmanial agent-11

SKU HY-147856-Get quote Category Tags , ,

Products Details

Product Description

– Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 28.3, 24.8 and 13.0 μM, respectively[1].

Web ID

– HY-147856

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H24ClN3O4

References

– [1]Pertino MW, et al. Synthesis, trypanocidal and anti-leishmania activity of new triazole-lapachol and nor-lapachol hybrids. Bioorg Chem. 2020 Oct;103:104122.

CAS Number

– 2253635-71-9

Molecular Weight

– 489.95

SMILES

– O=C(OC(C1=O)=C(C/C=C(C)C)C(C2=C1C=CC=C2)=O)CCCC3=CN(C4=CC=C(Cl)C=C4)N=N3

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Parasite

Isoform

– Leishmania

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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