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Antifungal agent 68
Products Details
Product Description
– Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51[1].
Web ID
– HY-155710
Shipping
– Room temperature
Molecular Formula
– C23H27ClN2O3
References
– [1]Campos Péret VA, et al. New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis. Eur J Med Chem. 2023 Aug 5;256:115436..
CAS Number
– 2925307-53-3
Molecular Weight
– 414.93
SMILES
– CCCC1=CC=C(OCC(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(OC)=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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