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Antifungal agent 31
Products Details
Product Description
– Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections[1].
Web ID
– HY-146079
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H22F2N6O3
References
– [1]Montoir D, et al. New azole antifungals with a fused triazinone scaffold. Eur J Med Chem. 2020 Mar 1;189:112082.
CAS Number
– 2077083-94-2
Molecular Weight
– 492.48
SMILES
– O=C1N([C@H](C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3)N=CC4=CC(C5=CC=C(OC)C=C5)=CN14
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
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