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Products Details
Product Description
– Anticancer agent 83 is a potent anticancer agent, inhibits LOX IMVI cells growth with a GI50 value of 0.15 mM. Anticancer agent 83 reduces mitochondrial membrane potential and induces DNA damage to induces leukemia cells apoptosis[1].
Web ID
– HY-151426
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H19N5OS
References
– [1]Pokhodylo N, et al. Novel N-(4-thiocyanatophenyl)-1H-1,2,3-triazole-4-carboxamides exhibit selective cytotoxic activity at nanomolar doses towards human leukemic T-cells. Eur J Med Chem. 2022 Nov 5;241:114633.
CAS Number
– 904815-29-8
Molecular Weight
– 377.46
SMILES
– O=C(C1=C(C)N(C2=CC=C(C(C)C)C=C2)N=N1)NC3=CC=C(SC#N)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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