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Product Description
– Anticancer agent 50 (compound 6) is a potent ABCB1 efflux pump modulator. Anticancer agent 50 shows cytotoxic effects and antiproliferative effects. Anticancer agent 50 decreases the expression of cyclin D1 and induces p53 expression. Anticancer agent 50 has the potential for the research of T-lymphoma[1].
Web ID
– HY-146389
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H32N2O4Se
References
– [1]Ali W, et al. Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma. Eur J Med Chem. 2020 Aug 15;200:112435.
CAS Number
– 2487457-15-6
Molecular Weight
– 563.55
SMILES
– COC(CN1C(N(C(C2=CC=CC=C2)(C1=O)C3=CC=CC=C3)CCCCCC[Se]C4=CC=CC=C4)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MDM-2/p53;P-glycoprotein
Pathway
– Apoptosis;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
