Download Files:
Products Details
Product Description
– Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].
Web ID
– HY-115980
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C50H65N5O10
References
– [1]Chen Zhou, et al. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A. Eur J Med Chem. 2022 Feb 5;229:114048.
CAS Number
– 2762426-00-4
Molecular Weight
– 896.08
SMILES
– O[C@@]([C@]1([H])C2=C)([H])[C@@]3(C2=O)[C@]([C@H](C1)O)([H])C4(CCCC(C)5C)[C@]5([H])C[C@@]3([H])O[C@H]4OCCCC(N=N6)=CN6CCOCCOCCOCCN(C7=O)C(C8=CC=C(N9CCCCC9)C%10=C8C7=CC=C%10)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
