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Products Details
Product Description
– Anticancer agent 124 is an orally active, highly selective and potent pan RAF inhibitor. Anticancer agent 124 inhibits MAPK signalling in BRAF V600E, NRAS and KRAS mutant tumor cells[1].
Web ID
– HY-108887
Shipping
– Room temperature
Molecular Formula
– C26H21ClN4O3
References
– [1]Helen Mason, et al. Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors. Cancer Res 1 July 2017; 77 (13_Supplement): 5160.
CAS Number
– 1884226-20-3
Molecular Weight
– 472.92
SMILES
– O=C1NC2=C(C(OC3=CC=C4C(CC(C5=NC=C(C6=CC=CC=C6Cl)N5)CO4)=C3)=CC=N2)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Raf
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
