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Antibacterial agent 98
Products Details
Product Description
– Antibacterial agent 98 (compound g37) is a potent and orally active antibacterial agent. Antibacterial agent 98 inhibits the ATPase activity of Gyrase B and impairs Staphylococcus aureus (S. aureus ) DNA supercoiling. Antibacterial agent 98 shows antibacterial activity and not induce resistance development of MRSA (methicillin-resistant S. aureus)[1].
Web ID
– HY-146403
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H13N5O3S2
References
– [1]Xue W, et al. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification. Eur J Med Chem. 2020 Feb 15;188:112022.
CAS Number
– 2408695-41-8
Molecular Weight
– 399.45
SMILES
– CCN1C(C(C(NC2=NN=C(S2)C3=NC=CS3)=O)=C(C4=C1C=CC=C4)O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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