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Antibacterial agent 145
Products Details
Product Description
– Antibacterial agent 145 (compound 1b) is an antibacterial agent depending on bacterial iron uptake pathway. Antibacterial agent 145 disrupts cytoplasmic membrane integrity and inhibits cell metabolism but exhibits low cytotoxic effects to normal cells[1].
Web ID
– HY-149353
Shipping
– Room temperature
Molecular Formula
– C30H33NO7
References
– [1]Huang YJ, et al. 3-Hydroxy-pyridin-4(1H)-ones as siderophores mediated delivery of isobavachalcone enhances antibacterial activity against pathogenic Pseudomonas aeruginosa. Eur J Med Chem. 2023 Sep 5;257:115454.
Molecular Weight
– 519.59
SMILES
– C/C(C)=C/CC1=C(O)C=CC(C(/C=C/C2=CC=C(OCCCOCC(N(C)C=C3O)=CC3=O)C=C2)=O)=C1O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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