Download Files:
Products Details
Product Description
– Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1].
Web ID
– HY-152250
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H14ClFN4OS
References
– [1]Asaf Evrim Evren，et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8(1):1410-1429.
Molecular Weight
– 412.87
SMILES
– COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=CC=CC(F)=C4)=CS3)=CC2=C1)Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Cytochrome P450
Isoform
– CYP19
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
