Antibacterial agent 130

SKU HY-152175-Get quote Category Tags , ,

Products Details

Product Description

– Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1].

Web ID

– HY-152175

Shipping

– Room temperature

Molecular Formula

– C23H28O10S

References

– [1]Bruneau A, et al. Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. Eur J Med Chem. 2022 Dec 15;247:115025.

CAS Number

– 1502721-60-9

Molecular Weight

– 496.53

SMILES

– OC[C@H]1O[C@@H](SC2=C(OC)C=CC(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)[C@H](O)[C@@H](O)[C@H]1O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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