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Products Details
Product Description
– Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs Staphylococcus aureus (S. aureus). Antibacterial agent 102 also moderately inhibits CYP3A4 with an IC50 value of 6.148 μM. Antibacterial agent 102 can reduce Methicillin-resistant Staphylococcus aureus (MRSA) load in thigh infected mice[1].
Web ID
– HY-146458
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C35H49N5O5S
References
– [1]Zhang Z, et al. Design, synthesis and biological activities of novel pleuromutilin derivatives with a substituted triazole moiety as potent antibacterial agents. Eur J Med Chem. 2020;204:112604.
CAS Number
– 2413293-65-7
Molecular Weight
– 651.86
SMILES
– O=C(O[C@H]1[C@]2(C)[C@@H](CC[C@]3([C@H]([C@@H]([C@](C=C)(C1)C)O)C)[C@]2(C(CC3)=O)[H])C)CSC4=C(NC(CN5C=C(CN(C)C)N=N5)=O)C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Cytochrome P450
Isoform
– CYP3
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
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