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Products Details
Product Description
– Antiangiogenic agent 2 (compound 3b) is a potent thymidine phosphorylase inhibitor, with an IC50 of 39.71 μM. Antiangiogenic agent 2 shows anti-angiogenic activity[1].
Web ID
– HY-147969
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H26FN3O4
References
– [1]Shahzad SA, et al. Synthesis, evaluation of thymidine phosphorylase and angiogenic inhibitory potential of ciprofloxacin analogues: Repositioning of ciprofloxacin from antibiotic to future anticancer drugs. Bioorg Chem. 2020 Jul;100:103876.
CAS Number
– 2422149-84-4
Molecular Weight
– 463.50
SMILES
– O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(CC5=CC=CC=C5)=O)CC4)=C3)C1=O)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
