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Anti-MI/R injury agent 1
Products Details
Product Description
– Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].
Web ID
– HY-130272
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C32H49NO6
References
– [1]Qiong Wu, et al. Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat. Eur J Med Chem. 2020 Jan 1;185:111729.
CAS Number
– 2387506-35-4
Molecular Weight
– 543.73
SMILES
– CC1(C)C2=C(C(C(O)=O)=NO2)C[C@@]3(C)C1[C@@H](O)C[C@]4(C)C3C[C@@H](O)C5[C@@]4(C)CC[C@]5([H])[C@@]6(C)CCCC(C)(C)O6
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
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