Anti-MI/R injury agent 1

SKU HY-130272-Get quote Category Tags ,

Products Details

Product Description

– Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R)-induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].

Web ID

– HY-130272

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C32H49NO6

References

– [1]Qiong Wu, et al. Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat. Eur J Med Chem. 2020 Jan 1;185:111729.

CAS Number

– 2387506-35-4

Molecular Weight

– 543.73

SMILES

– CC1(C)C2=C(C(C(O)=O)=NO2)C[C@@]3(C)C1[C@@H](O)C[C@]4(C)C3C[C@@H](O)C5[C@@]4(C)CC[C@]5([H])[C@@]6(C)CCCC(C)(C)O6

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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