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Products Details
Product Description
– Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active[1].
Web ID
– HY-115920
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H15N5OS2
References
– [1] Darwish SA, et al. New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies [published online ahead of print, 2022 Jan 29]. Bioorg Chem. 2022;120:105644.
CAS Number
– 1103920-19-9
Molecular Weight
– 381.47
SMILES
– O=C(C1=C(C)N2C3=CC=CC=C3N=C2S1)NNC(NC4=CC=CC=C4)=S
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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