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Products Details
Product Description
– Anti-inflammatory agent 7 inhibits proinflammatory cytokines by blocking the NF-κB/MAPK signaling pathway in LPS-treated RAW 264.7 cells as well as mice.
Web ID
– HY-139844
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C36H40N4O9
References
– [1]Bian M, et al. Design, Synthesis, and In Vitro and In Vivo Biological Evaluation of Limonin Derivatives for Anti-Inflammation Therapy. J Agric Food Chem. 2021 Nov 17;69(45):13487-13499.
Molecular Weight
– 672.72
SMILES
– O=C1[C@@H]2[C@]3(O2)[C@@]4(C)[C@]([C@]([C@@](C5)([H])OC6(C)C)(COC5=O)[C@@]6([H])C/C4=NOCC7=CN(C8=CC=C(OC)C=C8)N=N7)([H])CC[C@@]3(C)[C@H](C9=COC=C9)O1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB;p38 MAPK
Pathway
– MAPK/ERK Pathway;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
