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Products Details
Product Description
– Anti-inflammatory agent 66 (compound 8) is a pterostilbene derivative with anti-inflammatory activity. Anti-inflammatory agent 66 inhibits pro-inflammatory cytokines by blocking the LPS-induced NF-κB/MAPK signaling pathway and effectively alleviates DSS-induced acute colitis in mice[1].
Web ID
– HY-157211
Shipping
– Room temperature
Molecular Formula
– C24H25ClN4O4
References
– [1]Chen L et al. Design and synthesis of pterostilbene derivatives bearing triazole moiety that might treat DSS-induced colitis in mice through modulation of NF-κB/MAPK signaling pathways. Eur J Med Chem. 2023 Nov 17;263:115949.
Molecular Weight
– 468.93
SMILES
– C=CCOC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2C3=CN=NN3C(NCCCl)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB;p38 MAPK
Pathway
– MAPK/ERK Pathway;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
