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Products Details
Product Description
– Anti-inflammatory agent 66 (compound 8) is a pterostilbene derivative with anti-inflammatory activity. Anti-inflammatory agent 66 inhibits pro-inflammatory cytokines by blocking the LPS-induced NF-κB/MAPK signaling pathway and effectively alleviates DSS-induced acute colitis in mice[1].
Web ID
– HY-157211
Shipping
– Room temperature
Molecular Formula
– C24H25ClN4O4
References
– [1]Chen L et al. Design and synthesis of pterostilbene derivatives bearing triazole moiety that might treat DSS-induced colitis in mice through modulation of NF-κB/MAPK signaling pathways. Eur J Med Chem. 2023 Nov 17;263:115949.
Molecular Weight
– 468.93
SMILES
– C=CCOC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2C3=CN=NN3C(NCCCl)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB;p38 MAPK
Pathway
– MAPK/ERK Pathway;NF-κB
Product type
– Reference compound
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