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Products Details
Product Description
– Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD50: 1000 mg/kg)[1].
Web ID
– HY-155997
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H15F3N4O4S
References
– [1]Wang Y, et al. Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB. Eur J Med Chem. 2023 Nov 15;260:115742.
CAS Number
– 2413127-32-7
Molecular Weight
– 476.43
SMILES
– O=S(N)(C1=CC=C(N2N=C(C3=C(O)C=C(C(F)(F)F)C=C3)N=C2C4=C(O)C=CC=C4)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX
Isoform
– COX-2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
